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Univ Of Copenhagen Publish Malaria Paper In Journal Of Immunology Using Cellix's Platform

Univ of Copenhagen publish malaria paper in Journal of Immunology using Cellix's platform

Chondroitin Sulfate A-Adhering Plasmodium falciparum-Infected Erythrocytes Express Functionally Important Antibody Epitopes Shared by Multiple Variants

Lea Barfod, Tina Dobrilovic, Pamela Magistrado, Pongsak, Khunrae,
Firmine Viwami, Jonas Bruun, Madeleine Dahlback, Nadia L. Bernasconi,
Michal Fried, Davis John, Patrick E. Dufy, Ali Salanti, Antonio Lanzavecchia,
Chwee Teck Lim, Nicaise Tuikue Ndam, Matthew K. Higgins and Lars Hviid.* 
 

Using the Cellix Ltd VenaFluxTM Platform to perform flow assays, together with static assays,  were employed to evaluated the capacity of the human mAbs to interfere with CSA-specific adhesion of the infected erythrocytes (IEs).  Overall, results underpin the hypothesis that few Ab specificities are sufficient to substantially interfere with receptor-specific adhesion of IEs to CSA.

 

*Centre for Medical Parasitology, Department of International Health, Immunology, and Microbiology, University of Copenhagen.
 

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